2ATR
 
 | Acetyltransferase, GNAT family protein SP0256 from Streptococcus pneumoniae TIGR4 | Descriptor: | acetyltransferase, GNAT family | Authors: | Binkowski, T.A, Hatzos, C, Abdullah, J, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-08-25 | Release date: | 2005-10-11 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Acetyltransferase, GNAT family protein SP0256 from Streptococcus pneumoniae To be Published
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3E64
 
 | Fragment based discovery of JAK-2 inhibitors | Descriptor: | 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide, Tyrosine-protein kinase JAK2 | Authors: | Antonysamy, S, Fang, W, Hirst, G, Park, F, Russell, M, Smyth, L, Sprengeler, P, Stappenbeck, F, Steensma, R, Thompson, D.A, Wilson, M, Wong, M, Zhang, A, Zhang, F. | Deposit date: | 2008-08-14 | Release date: | 2008-10-14 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fragment-based discovery of JAK-2 inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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3EYO
 
 | Crystal structure of anti-human cytomegalovirus antibody 8F9 | Descriptor: | 8f9 Fab, AD-2 | Authors: | Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. | Deposit date: | 2008-10-21 | Release date: | 2008-12-16 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27, 2008
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3F12
 
 | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus | Descriptor: | 8f9 Fab, M2J1 Fab | Authors: | Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. | Deposit date: | 2008-10-27 | Release date: | 2009-09-15 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27, 2008
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3I91
 
 | Crystal structure of human chromobox homolog 8 (CBX8) with H3K9 peptide | Descriptor: | Chromobox protein homolog 8, H3K9 peptide | Authors: | Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-07-10 | Release date: | 2009-09-08 | Last modified: | 2025-03-26 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
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7K3X
 
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8TT9
 
 | X-ray structure of Macrophage Migration Inhibitory Factor (MIF) Covalently Bound to 4-hydroxyphenylpyruvate (HPP) | Descriptor: | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor | Authors: | Schroder, G.C, Meilleur, F, Nix, J.C, Crichlow, G.V, Lolis, E.J. | Deposit date: | 2023-08-13 | Release date: | 2024-08-28 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | X-ray structure of Macrophage Migration Inhibitory Factor (MIF) Covalently Bound to 4-hydroxyphenylpyruvate (HPP) To Be Published
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9IR5
 
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9IR6
 
 | Crystal structure of UDP-N-acetylmuramic Acid L-alanine ligase (MurC) from Roseburia faecis in complex with UNAM | Descriptor: | (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, 1,2-ETHANEDIOL, UDP-N-acetylmuramate--L-alanine ligase | Authors: | Wang, Y.X, Du, Y.H. | Deposit date: | 2024-07-14 | Release date: | 2025-04-09 | Last modified: | 2025-06-11 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Unusual MurC Ligase and Peptidoglycan Discovered in Lachnospiraceae Using a Fluorescent L-Amino Acid Based Selective Labeling Probe. Angew.Chem.Int.Ed.Engl., 64, 2025
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9LSW
 
 | Crystal structure of the calcium-free mRFP1 with a grafted calcium-binding sequence | Descriptor: | Red fluorescent protein,grafted calcium-binding sequence | Authors: | Uehara, R, Kamiya, Y, Maeda, S, Okamoto, K, Toya, S, Chiba, R, Amesaka, H, Takano, K, Matsumura, H, Tanaka, S.-i. | Deposit date: | 2025-02-05 | Release date: | 2025-06-04 | Last modified: | 2025-06-11 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | Enhanced secretion through type 1 secretion system by grafting a calcium-binding sequence to modify the folding of cargo proteins. Protein Sci., 34, 2025
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