8V7J
 
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8V7F
 
 | Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mn2+ | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T*())-3'), DNA (5'-D(*CP*AP*TP*GP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2023-12-04 | Release date: | 2024-05-15 | Last modified: | 2025-06-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Sugar ring alignment and dynamics underline cytarabine and gemcitabine inhibition on Pol eta catalyzed DNA synthesis. J.Biol.Chem., 300, 2024
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8V7H
 
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8V7B
 
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8V7D
 
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8V7G
 
 | Human DNA polymerase eta-DNA-gemC-ended primer-dAMPNPP ternary complex with Mg2+ | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*(U7B))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2023-12-04 | Release date: | 2024-05-15 | Last modified: | 2025-06-04 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Sugar ring alignment and dynamics underline cytarabine and gemcitabine inhibition on Pol eta catalyzed DNA synthesis. J.Biol.Chem., 300, 2024
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8VNU
 
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8VMS
 
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8VN3
 
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8VND
 
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8VNM
 
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8VMU
 
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8VN5
 
 | Homing endonuclease I-PpoI-DNA complex:ground state at pH8.0 (Tris) with Na+ | Descriptor: | DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2024-01-13 | Release date: | 2024-07-10 | Last modified: | 2025-01-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Observing one-divalent-metal-ion-dependent and histidine-promoted His-Me family I-PpoI nuclease catalysis in crystallo. Elife, 13, 2024
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8VNC
 
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8VNP
 
 | Homing endonuclease I-PpoI-DNA complex at pH6.0 (K+ MES) with 0.2 M sodium malonate | Descriptor: | DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2024-01-13 | Release date: | 2024-07-10 | Last modified: | 2025-01-29 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Observing one-divalent-metal-ion-dependent and histidine-promoted His-Me family I-PpoI nuclease catalysis in crystallo. Elife, 13, 2024
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8VMQ
 
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8VN0
 
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8VN9
 
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8VNN
 
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8VMP
 
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8VMZ
 
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8VNA
 
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8VNK
 
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8VN8
 
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8VNJ
 
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