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PDB: 158 results
1B2W
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BU of 1b2w by Molmil
COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY
Descriptor: PROTEIN (ANTIBODY (HEAVY CHAIN)), PROTEIN (ANTIBODY (LIGHT CHAIN))
Authors:Fan, Z, Shan, L, Goldsteen, B.Z, Guddat, L.W, Thakur, A, Landolfi, N.F, Co, M.S, Vasquez, M, Queen, C, Ramsland, P.A, Edmundson, A.B.
Deposit date:1998-12-01
Release date:1999-05-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
J.Mol.Recog., 12, 1999
1B4J
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BU of 1b4j by Molmil
COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY
Descriptor: ANTIBODY
Authors:Fan, Z, Shan, L, Goldsteen, B.Z, Guddat, L.W, Thakur, A, Landolfi, N.F, Co, M.S, Vasques, M, Queen, C, Ramsland, P.A, Edmundson, A.B.
Deposit date:1998-12-22
Release date:1999-06-15
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
J.Mol.Recog., 12, 1999
1IGM
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BU of 1igm by Molmil
THREE DIMENSIONAL STRUCTURE OF AN FV FROM A HUMAN IGM IMMUNOGLOBULIN
Descriptor: IGM-KAPPA POT FV (HEAVY CHAIN), IGM-KAPPA POT FV (LIGHT CHAIN)
Authors:Fan, Z.-C, Guddat, L.W, Edmundson, A.B.
Deposit date:1992-07-10
Release date:1993-10-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structure of an Fv from a human IgM immunoglobulin.
J.Mol.Biol., 228, 1992
5W7N
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BU of 5w7n by Molmil
2-Se-T2/4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant
Descriptor: DNA (5'-D(*AP*(US3)P*GP*(US3)P*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ...
Authors:Fang, Z, Yang, F, Huang, Z.
Deposit date:2017-06-20
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:2-Se-T2/4-modified-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant
To Be Published
9F17
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BU of 9f17 by Molmil
Crystal structure of N term His-tag Adenylosuccinate synthetase from Helicobacter pylori
Descriptor: Adenylosuccinate synthetase, CALCIUM ION, GLYCEROL, ...
Authors:Stefanic, Z.
Deposit date:2024-04-18
Release date:2024-09-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Location Is Everything: Influence of His-Tag Fusion Site on Properties of Adenylosuccinate Synthetase from Helicobacter pylori.
Int J Mol Sci, 25, 2024
9CSR
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BU of 9csr by Molmil
16mer self-complementary duplex RNA with s(2)C:I pair sequence 2
Descriptor: RNA strand with s(2)C:I pair sequence 2
Authors:Fang, Z, Jia, X, Szostak, J.W.
Deposit date:2024-07-24
Release date:2025-05-14
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Nonenzymatic RNA copying with a potentially primordial genetic alphabet.
Proc.Natl.Acad.Sci.USA, 122, 2025
9MDX
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BU of 9mdx by Molmil
16mer self-complementary duplex RNA with s(2)U:A pair sequence 1
Descriptor: RNA strand with s(2)U:A pair sequence 1
Authors:Fang, Z, Jia, X, Szostak, J.W.
Deposit date:2024-12-05
Release date:2025-05-14
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Nonenzymatic RNA copying with a potentially primordial genetic alphabet.
Proc.Natl.Acad.Sci.USA, 122, 2025
9MDW
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BU of 9mdw by Molmil
16mer self-complementary duplex RNA with all Watson-Crick base pairs
Descriptor: 16mer RNA strand with all Watson-Crick base pairs, MAGNESIUM ION
Authors:Fang, Z, Jia, X, Szostak, J.W.
Deposit date:2024-12-05
Release date:2025-05-14
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.421 Å)
Cite:Nonenzymatic RNA copying with a potentially primordial genetic alphabet.
Proc.Natl.Acad.Sci.USA, 122, 2025
9MDY
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BU of 9mdy by Molmil
16mer self-complementary duplex RNA with s(2)U:A pair sequence 2
Descriptor: MAGNESIUM ION, RNA strand with s(2)U:A pair sequence 2
Authors:Fang, Z, Jia, X, Szostak, J.W.
Deposit date:2024-12-05
Release date:2025-05-14
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Nonenzymatic RNA copying with a potentially primordial genetic alphabet.
Proc.Natl.Acad.Sci.USA, 122, 2025
9CSQ
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BU of 9csq by Molmil
16mer self-complementary duplex RNA with s(2)C:I pair sequence 1
Descriptor: RNA strand with s(2)C:I pair sequence 1
Authors:Fang, Z, Jia, X, Szostak, J.W.
Deposit date:2024-07-24
Release date:2025-05-14
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Nonenzymatic RNA copying with a potentially primordial genetic alphabet.
Proc.Natl.Acad.Sci.USA, 122, 2025
9CSO
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BU of 9cso by Molmil
16mer self-complementary duplex RNA with s(2)C:G pair sequence 1
Descriptor: RNA strand with s(2)C:G pair sequence 1
Authors:Fang, Z, Jia, X, Szostak, J.W.
Deposit date:2024-07-24
Release date:2025-05-14
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Nonenzymatic RNA copying with a potentially primordial genetic alphabet.
Proc.Natl.Acad.Sci.USA, 122, 2025
5W7O
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BU of 5w7o by Molmil
2-Se-T4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant
Descriptor: DNA (5'-D(*AP*TP*GP*(US3)P*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ...
Authors:Fang, Z, Yang, F, Huang, Z.
Deposit date:2017-06-20
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:2-Se-T-modified-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant
To Be Published
5WJR
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BU of 5wjr by Molmil
High resolution native hexamer DNA and RNA hybrid in complex with RNase H catalytic domain D132N mutant
Descriptor: DNA (5'-D(*AP*TP*GP*TP*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ...
Authors:Fang, Z, Huang, Z.
Deposit date:2017-07-24
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Chemistryselect, 8, 2023
8TDY
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BU of 8tdy by Molmil
16mer self-complementary duplex RNA with D:U pair sequence 1
Descriptor: MAGNESIUM ION, RNA
Authors:Fang, Z, Jia, X, Szostak, J.W.
Deposit date:2023-07-05
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Diaminopurine in Nonenzymatic RNA Template Copying.
J.Am.Chem.Soc., 146, 2024
8TE2
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BU of 8te2 by Molmil
16mer self-complementary duplex RNA with D:C pair sequence 2
Descriptor: CALCIUM ION, RNA
Authors:Fang, Z, Jia, X, Szostak, J.W.
Deposit date:2023-07-05
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Diaminopurine in Nonenzymatic RNA Template Copying.
J.Am.Chem.Soc., 146, 2024
6CCX
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BU of 6ccx by Molmil
NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc
Descriptor: (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ...
Authors:Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M.
Deposit date:2018-02-07
Release date:2018-09-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site.
Cell Chem Biol, 25, 2018
6CCH
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BU of 6cch by Molmil
NMR data-driven model of GTPase KRas-GMPPNP tethered to a nanodisc (E3 state)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ...
Authors:Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M.
Deposit date:2018-02-07
Release date:2018-08-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site.
Cell Chem Biol, 25, 2018
8VAW
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BU of 8vaw by Molmil
Magnesium catalyzed primer extension product with 14mer primer and mixed phosphorothioate activated G monomer
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, Magnesium catalyzed nonenzymatic RNA primer extension product
Authors:Fang, Z, Szostak, J.W.
Deposit date:2023-12-11
Release date:2024-04-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 146, 2024
8SCP
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BU of 8scp by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 1h
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
Authors:Fang, Z, Lelyveld, V.S, Szostak, J.W.
Deposit date:2023-04-05
Release date:2023-10-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCR
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BU of 8scr by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 4h
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
Authors:Fang, Z, Lelyveld, V.S, Szostak, J.W.
Deposit date:2023-04-05
Release date:2023-10-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCQ
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BU of 8scq by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 2h
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
Authors:Fang, Z, Lelyveld, V.S, Szostak, J.W.
Deposit date:2023-04-05
Release date:2023-10-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCS
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BU of 8scs by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 8h
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
Authors:Fang, Z, Lelyveld, V.S, Szostak, J.W.
Deposit date:2023-04-05
Release date:2023-10-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCT
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BU of 8sct by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 24h
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
Authors:Fang, Z, Lelyveld, V.S, Szostak, J.W.
Deposit date:2023-04-05
Release date:2023-10-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8FEO
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BU of 8feo by Molmil
16mer self-complementary duplex RNA with two separated native U:U pairs
Descriptor: MAGNESIUM ION, RNA 16mer, STRONTIUM ION
Authors:Fang, Z, Szostak, J.W.
Deposit date:2022-12-06
Release date:2024-01-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying.
J.Am.Chem.Soc., 146, 2024
8FEP
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BU of 8fep by Molmil
16mer self-complementary duplex RNA with two continuous native U:U pairs
Descriptor: RNA 16mer
Authors:Fang, Z, Szostak, J.W.
Deposit date:2022-12-06
Release date:2024-01-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying.
J.Am.Chem.Soc., 146, 2024

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