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PDB: 331 results

3REM
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BU of 3rem by Molmil
Structure of the Isochorismate-Pyruvate Lyase from Pseudomonas aerugionsa with Bound Salicylate and Pyruvate
Descriptor: 2-HYDROXYBENZOIC ACID, PYRUVIC ACID, Salicylate biosynthesis protein pchB
Authors:Olucha, J, Ouellette, A.N, Luo, Q, Lamb, A.L.
Deposit date:2011-04-04
Release date:2011-07-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:pH Dependence of Catalysis by Pseudomonas aeruginosa Isochorismate-Pyruvate Lyase: Implications for Transition State Stabilization and the Role of Lysine 42.
Biochemistry, 50, 2011
3RA7
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BU of 3ra7 by Molmil
Bispecific digoxigenin binding antibodies for targeted payload delivery
Descriptor: DIGOXIGENIN, Fab fragment, heavy chain, ...
Authors:Hopfner, K.P, Lammens, A.
Deposit date:2011-03-27
Release date:2011-07-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:Bispecific digoxigenin-binding antibodies for targeted payload delivery
Proc.Natl.Acad.Sci.USA, 108, 2011
3RET
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BU of 3ret by Molmil
Salicylate and Pyruvate Bound Structure of the Isochorismate-Pyruvate Lyase K42E Mutant from Pseudomonas aerugionsa
Descriptor: 2-HYDROXYBENZOIC ACID, PYRUVIC ACID, Salicylate biosynthesis protein pchB
Authors:Olucha, J, Ouellette, A.N, Luo, Q, Lamb, A.L.
Deposit date:2011-04-05
Release date:2011-07-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:pH Dependence of Catalysis by Pseudomonas aeruginosa Isochorismate-Pyruvate Lyase: Implications for Transition State Stabilization and the Role of Lysine 42.
Biochemistry, 50, 2011
3OH2
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BU of 3oh2 by Molmil
Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE-GALACTOSE
Descriptor: GALACTOSE-URIDINE-5'-DIPHOSPHATE, GLYCEROL, UDP-sugar pyrophosphorylase
Authors:Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R.
Deposit date:2010-08-17
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major.
J.Mol.Biol., 405, 2011
3OH3
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BU of 3oh3 by Molmil
Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE -Arabinose
Descriptor: GLYCEROL, UDP-sugar pyrophosphorylase, [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl dihydrogen diphosphate
Authors:Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R.
Deposit date:2010-08-17
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major.
J.Mol.Biol., 405, 2011
3OH4
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BU of 3oh4 by Molmil
Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE Glucose
Descriptor: GLYCEROL, UDP-sugar pyrophosphorylase, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F.H, Ficner, R.
Deposit date:2010-08-17
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major.
J.Mol.Biol., 405, 2011
3OH1
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BU of 3oh1 by Molmil
Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE-Galacturonic acid
Descriptor: (2S,3R,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic acid, GLYCEROL, UDP-sugar pyrophosphorylase
Authors:Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R.
Deposit date:2010-08-17
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major.
J.Mol.Biol., 405, 2011
3OH0
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BU of 3oh0 by Molmil
Protein structure of USP from L. major bound to URIDINE-5'-TRIPHOSPHATE
Descriptor: GLYCEROL, UDP-sugar pyrophosphorylase, URIDINE 5'-TRIPHOSPHATE
Authors:Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R.
Deposit date:2010-08-17
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major.
J.Mol.Biol., 405, 2011
3E8H
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BU of 3e8h by Molmil
Crystal Structure of the the open NaK channel-K+ complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein
Authors:Jiang, Y, Alam, A.
Deposit date:2008-08-19
Release date:2008-12-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of ion selectivity in the NaK channel
Nat.Struct.Mol.Biol., 16, 2009
3E8F
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BU of 3e8f by Molmil
Crystal Structure of the the open NaK channel- K+/Ba2+
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, BARIUM ION, POTASSIUM ION, ...
Authors:Jiang, Y, Alam, A.
Deposit date:2008-08-19
Release date:2008-12-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of ion selectivity in the NaK channel
Nat.Struct.Mol.Biol., 16, 2009
3Q5K
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BU of 3q5k by Molmil
Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor
Descriptor: 4-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]-2-{[2-(methylsulfanyl)ethyl]amino}benzamide, Heat shock protein 83-1
Authors:Wernimont, A.K, Tempel, W, Lin, Y.H, Hutchinson, A, MacKenzie, F, Fairlamb, A, Cossar, D, Zhao, Y, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC)
Deposit date:2010-12-28
Release date:2011-02-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor
To be Published
3E8B
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BU of 3e8b by Molmil
Crystal Structure of the the open NaK channel- Rb+ complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein, RUBIDIUM ION
Authors:Jiang, Y, Alam, A.
Deposit date:2008-08-19
Release date:2008-12-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of ion selectivity in the NaK channel
Nat.Struct.Mol.Biol., 16, 2009
3PP3
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BU of 3pp3 by Molmil
Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for the type I / type II distinction of anti- CD20 antibodies
Descriptor: GA101 Fab heavy chain, GA101 Fab light chain
Authors:Hopfner, K.-P, Lammens, A.
Deposit date:2010-11-24
Release date:2011-04-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.508 Å)
Cite:Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies.
Blood, 118, 2011
4Z1X
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BU of 4z1x by Molmil
Crystal structure of LAGLIDADG homing endonuclease I-GzeII in complex with DNA target
Descriptor: CALCIUM ION, DNA (27-MER), LAGLIDADG endonuclease
Authors:Stoddard, B.L, Lambert, A.R, Kulshina, N.
Deposit date:2015-03-27
Release date:2015-04-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of LAGLIDADG homing endonuclease I-GzeII in complex with DNA target
To Be Published
3I61
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BU of 3i61 by Molmil
Structure of Mss116p bound to ssRNA and ADP-Beryllium Fluoride
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2009-07-06
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA
Mol.Cell, 35, 2009
3E89
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BU of 3e89 by Molmil
Crystal Structure of the the open NaK channel-low Na+ complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CESIUM ION, Potassium channel protein, ...
Authors:Jiang, Y, Alam, A.
Deposit date:2008-08-19
Release date:2008-12-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of ion selectivity in the NaK channel
Nat.Struct.Mol.Biol., 16, 2009
3E8G
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BU of 3e8g by Molmil
Crystal Structure of the the open NaK channel-Na+/Ca2+ complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CESIUM ION, ...
Authors:Jiang, Y, Alam, A.
Deposit date:2008-08-19
Release date:2008-12-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of ion selectivity in the NaK channel
Nat.Struct.Mol.Biol., 16, 2009
7ZY6
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BU of 7zy6 by Molmil
Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST
Descriptor: 5-imidazo[1,2-a]pyridin-3-yl-~{N}-[(1~{R})-1-(6-pyrrolidin-1-ylpyridin-3-yl)ethyl]pyridin-3-amine, HUMAN PROTO-ONCOGENE C-KIT
Authors:Graedler, U, Lammens, A.
Deposit date:2022-05-24
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Identification of M4205─A Highly Selective Inhibitor of KIT Mutations for Treatment of Unresectable Metastatic or Recurrent Gastrointestinal Stromal Tumors.
J.Med.Chem., 66, 2023
3OGZ
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BU of 3ogz by Molmil
Protein structure of USP from L. major in Apo-form
Descriptor: GLYCEROL, UDP-sugar pyrophosphorylase
Authors:Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R.
Deposit date:2010-08-17
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major.
J.Mol.Biol., 405, 2011
3I62
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BU of 3i62 by Molmil
Structure of Mss116p bound to ssRNA and ADP-Aluminum Fluoride
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2009-07-06
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA
Mol.Cell, 35, 2009
7ZW8
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BU of 7zw8 by Molmil
Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST
Descriptor: Mast/stem cell growth factor receptor Kit, ~{N}-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine
Authors:Graedler, U, Lammens, A.
Deposit date:2022-05-19
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.119 Å)
Cite:Identification of M4205─A Highly Selective Inhibitor of KIT Mutations for Treatment of Unresectable Metastatic or Recurrent Gastrointestinal Stromal Tumors.
J.Med.Chem., 66, 2023
3PP4
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BU of 3pp4 by Molmil
Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for the type I / type II distinction of anti- CD20 antibodies
Descriptor: B-lymphocyte antigen CD20, CHLORIDE ION, GA101 Fab heavy chain, ...
Authors:Hopfner, K.-P, Lammens, A.
Deposit date:2010-11-24
Release date:2011-04-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies.
Blood, 118, 2011
3HHP
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BU of 3hhp by Molmil
Malate dehydrogenase open conformation
Descriptor: Malate dehydrogenase
Authors:Zaitseva, J, Meneely, K.M, Lamb, A.L.
Deposit date:2009-05-15
Release date:2009-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of Escherichia coli malate dehydrogenase at 1.45 A resolution.
Acta Crystallogr.,Sect.F, 65, 2009
3Q5L
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BU of 3q5l by Molmil
Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin
Descriptor: (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-{[2-(pyrrolidin-1-yl)ethyl]amino}-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, Heat shock protein 83-1
Authors:Wernimont, A.K, Tempel, W, Lin, Y.H, Hutchinson, A, MacKenzie, F, Fairlamb, A, Cossar, D, Zhao, Y, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC)
Deposit date:2010-12-28
Release date:2011-02-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin.
To be Published
8AW1
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BU of 8aw1 by Molmil
c-MET Y1235D mutant in complex with Tepotinib
Descriptor: 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile, Hepatocyte growth factor receptor
Authors:Graedler, U, Lammens, A.
Deposit date:2022-08-29
Release date:2023-09-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding.
J.Biol.Chem., 299, 2023

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