9J1C
 
 | | Structure of ConA/NAP-Man | | Descriptor: | CALCIUM ION, Concanavalin-A, MANGANESE (II) ION, ... | | Authors: | Li, L, Chen, G. | | Deposit date: | 2024-08-04 | | Release date: | 2024-12-04 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Structure of ConA/NAP-Man
To Be Published
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9J1F
 | | Dimeric Structure of ConA/M2P-Man | | Descriptor: | CALCIUM ION, Concanavalin-A, MANGANESE (II) ION, ... | | Authors: | Li, L, Chen, G. | | Deposit date: | 2024-08-04 | | Release date: | 2024-12-04 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Dimeric Structure of ConA/M2P-Man
To Be Published
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8W8N
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8W8P
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8W8O
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3KJR
 | | Crystal structure of dihydrofolate reductase/thymidylate synthase from Babesia bovis determined using SlipChip based microfluidics | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Dihydrofolate reductase/thymidylate synthase, GLYCEROL, ... | | Authors: | Li, L, Du, W, Edwards, T.E, Staker, B.L, Phan, I, Stacy, R, Ismagilov, R.F, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2009-11-03 | | Release date: | 2009-11-17 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Multiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods.
J.Am.Chem.Soc., 132, 2010
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3C6E
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8YF2
 | | Cryo-EM structure of SARS-CoV-2 prototype RBD in complex with raccoon dog ACE2 (local refinement) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | Authors: | Li, L.J, Luo, C.L, Qi, J.X, Gao, G.F. | | Deposit date: | 2024-02-23 | | Release date: | 2024-10-23 | | Last modified: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.64 Å) | | Cite: | Receptor binding and structural basis of raccoon dog ACE2 binding to SARS-CoV-2 prototype and its variants.
Plos Pathog., 20, 2024
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8YFT
 | | Cryo-EM structure of SARS-CoV-2 alpha variant spike protein in complex with raccoon dog ACE2 (local refinement) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | Authors: | Li, L.J, Luo, C.L, Qi, J.X, Gao, G.F. | | Deposit date: | 2024-02-25 | | Release date: | 2024-10-23 | | Last modified: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Receptor binding and structural basis of raccoon dog ACE2 binding to SARS-CoV-2 prototype and its variants.
Plos Pathog., 20, 2024
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3IPZ
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7N8T
 | | Crystal Structure of AMP-bound Human JNK2 | | Descriptor: | ADENOSINE MONOPHOSPHATE, HEXAETHYLENE GLYCOL, Mitogen-activated protein kinase 9 | | Authors: | Li, L, Gurbani, D, Westover, K.D. | | Deposit date: | 2021-06-15 | | Release date: | 2022-06-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1.
J.Med.Chem., 66, 2023
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3DAM
 | | Crystal Structure of Allene oxide synthase | | Descriptor: | Cytochrome P450 74A2, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Li, L, Wang, X. | | Deposit date: | 2008-05-29 | | Release date: | 2008-09-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C6D
 | | The pseudo-atomic structure of dengue immature virus | | Descriptor: | Polyprotein, prM | | Authors: | Li, L. | | Deposit date: | 2008-02-04 | | Release date: | 2008-04-08 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (12.5 Å) | | Cite: | The flavivirus precursor membrane-envelope protein complex: structure and maturation
Science, 319, 2008
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7XB0
 | | Crystal structure of Omicron BA.2 RBD complexed with hACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Li, L, Liao, H, Meng, Y, Li, W. | | Deposit date: | 2022-03-19 | | Release date: | 2022-07-06 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.
Cell, 185, 2022
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3C5X
 | | Crystal structure of the precursor membrane protein- envelope protein heterodimer from the dengue 2 virus at low pH | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-altropyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Li, L. | | Deposit date: | 2008-02-01 | | Release date: | 2008-04-08 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The flavivirus precursor membrane-envelope protein complex: structure and maturation.
Science, 319, 2008
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8WP8
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | | Authors: | Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. | | Deposit date: | 2023-10-09 | | Release date: | 2024-07-03 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2
To Be Published
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8WOY
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with rabbit ACE2 (local refinement) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | | Authors: | Li, L.J, Shi, K.Y, Yu, G.H, Gao, G.F. | | Deposit date: | 2023-10-08 | | Release date: | 2023-12-13 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency.
Mbio, 15, 2024
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8WOZ
 | | Cryo-EM structure of SARS-CoV RBD in complex with rabbit ACE2 | | Descriptor: | Angiotensin-converting enzyme, Spike protein S1, ZINC ION | | Authors: | Li, L.J, Shi, K.Y, Yu, G.H, Gao, G.F. | | Deposit date: | 2023-10-08 | | Release date: | 2023-12-13 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency.
Mbio, 15, 2024
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8WOX
 | | Cryo-EM structure of SARS-CoV-2 prototype RBD in complex with rabbit ACE2 (local refinement) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | | Authors: | Li, L.J, Shi, K.Y, Yu, G.H, Gao, G.F. | | Deposit date: | 2023-10-08 | | Release date: | 2023-12-13 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency.
Mbio, 15, 2024
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3DAN
 | | Crystal Structure of Allene oxide synthase | | Descriptor: | Cytochrome P450 74A2, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Li, L, Wang, X. | | Deposit date: | 2008-05-29 | | Release date: | 2008-09-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3DBM
 | | Crystal Structure of Allene oxide synthase | | Descriptor: | (9E,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid, Cytochrome P450 74A2, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Li, L, Wang, X. | | Deposit date: | 2008-06-01 | | Release date: | 2008-09-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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4E5X
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5ZX3
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5ZX2
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5DXY
 | | Crystal structure of Dbr2 | | Descriptor: | Artemisinic aldehyde Delta(11(13)) reductase, FLAVIN MONONUCLEOTIDE, [[(2R,3S,4R,5R)-5-(5-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | | Authors: | Li, L, Chen, T.T, Xu, Y.C. | | Deposit date: | 2015-09-24 | | Release date: | 2016-10-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | The Crystal structure of Dbr2
to be published
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