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PDB: 44 件

1W3E
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Ribosomal L30e of Thermococcus celer, P59A mutant
分子名称: 50S RIBOSOMAL PROTEIN L30E
著者Ma, H.W, Lee, C.F, Allen, M.D, Bycroft, M, Wong, K.B.
登録日2004-07-15
公開日2006-10-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Role of Proline Residues in Thermostability of T. Celer L30E Protein
To be Published
8WMI
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BU of 8wmi by Molmil
Cryo-EM structure of DiCas7-11 mutant in complex with crRNA
分子名称: CRISPR-associated RAMP family protein, ZINC ION, crRNA (39-MER)
著者Ma, H.Y, Tang, X.D.
登録日2023-10-03
公開日2024-05-29
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
8WM4
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Cryo-EM structure of DiCas7-11 in complex with crRNA
分子名称: CRISPR-associated RAMP family protein, ZINC ION, crRNA (38-MER)
著者Ma, H.Y, Tang, X.D.
登録日2023-10-02
公開日2024-05-29
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
8WML
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BU of 8wml by Molmil
Cryo-EM structure of Cas7-11-crRNA bound to N-terminal of TPR-CHAT
分子名称: CHAT domain-containing protein, CRISPR-associated RAMP family protein, ZINC ION, ...
著者Ma, H.Y, Tang, X.D.
登録日2023-10-03
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
8WMC
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BU of 8wmc by Molmil
Cryo-EM structure of DiCas7-11-crRNA in complex with regulator
分子名称: CHAT domain-containing protein, CRISPR-associated RAMP family protein, RNA (38-MER), ...
著者Ma, H.Y, Tang, X.D.
登録日2023-10-03
公開日2024-05-29
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
5HRJ
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BU of 5hrj by Molmil
Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163
分子名称: Scavenger receptor cysteine-rich type 1 protein M130
著者Ma, H, Jiang, L, Qiao, S, Zhang, G, Li, R.
登録日2016-01-23
公開日2017-07-19
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163
To Be Published
5JFB
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BU of 5jfb by Molmil
Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163
分子名称: Scavenger receptor cysteine-rich type 1 protein M130
著者Ma, H, Jiang, L, Qiao, S, Zhang, G, Li, R.
登録日2016-04-19
公開日2017-03-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain of Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus Infection
J. Virol., 91, 2017
5IRI
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BU of 5iri by Molmil
Structure of the mouse SAD-B AIS-KA1 fragment
分子名称: Serine/threonine-protein kinase BRSK1
著者Ma, H, Wu, J.X, Wang, J, Wu, J.W.
登録日2016-03-13
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and inhibition analysis of the mouse SAD-B C-terminal fragment
Biosci.Biotechnol.Biochem., 2016
7X4I
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BU of 7x4i by Molmil
Crystal structure of nanobody aSA3 in complex with dimer SARS-CoV-1 RBD
分子名称: Spike glycoprotein, nanobody aSA3
著者Ma, H, Zeng, W.H, Jin, T.C.
登録日2022-03-02
公開日2023-01-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献A bispecific nanobody dimer broadly neutralizes SARS-CoV-1 & 2 variants of concern and offers substantial protection against Omicron via low-dose intranasal administration.
Cell Discov, 8, 2022
7C2E
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GLP-1R-Gs complex structure with a small molecule full agonist
分子名称: 2-[[4-[6-[(4-cyano-2-fluoranyl-phenyl)methoxy]pyridin-2-yl]-3,6-dihydro-2~{H}-pyridin-1-yl]methyl]-3-[[(2~{S})-oxetan-2-yl]methyl]imidazo[4,5-b]pyridine-5-carboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Ma, H, Yuan, D.P, Huang, W, Wenge, Z, Xu, E.
登録日2020-05-07
公開日2020-08-26
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insights into the activation of GLP-1R by a small molecule agonist.
Cell Res., 30, 2020
7VOA
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BU of 7voa by Molmil
Crystal structure of SARS-CoV-2 RBD in complex with aRBD5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpaca nanobody
著者Ma, H, Zeng, W.H, Jin, T.C.
登録日2021-10-13
公開日2022-08-10
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron.
Cell Res., 32, 2022
6K0L
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BU of 6k0l by Molmil
The crystal structure of simian CD163 SRCR5
分子名称: Scavenger receptor cysteine-rich type 1 protein M130
著者Ma, H, Li, R, Jiang, L, Qiao, S, Zhang, G.
登録日2019-05-07
公開日2020-05-13
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural comparison of CD163 SRCR5 from different species sheds some light on its involvement in porcine reproductive and respiratory syndrome virus-2 infection in vitro.
Vet Res, 52, 2021
6K0O
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BU of 6k0o by Molmil
The crystal structure of human CD163-like homolog SRCR8
分子名称: Scavenger receptor cysteine-rich type 1 protein M160
著者Ma, H, Li, R, Jiang, L, Qiao, S, Zhang, G.
登録日2019-05-07
公開日2020-05-13
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural comparison of CD163 SRCR5 from different species sheds some light on its involvement in porcine reproductive and respiratory syndrome virus-2 infection in vitro.
Vet Res, 52, 2021
7XUY
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BU of 7xuy by Molmil
Crystal structure of 5-chloro-2-hydroxymuconate tautomerase CnbG
分子名称: Tautomerase
著者Ma, H.L, Li, D.F.
登録日2022-05-20
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural insights into the substrate specificity of 5-chloro-2-hydroxymuconate tautomerase CnbG.
Biochem.Biophys.Res.Commun., 620, 2022
1AFS
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BU of 1afs by Molmil
RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE
分子名称: 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TESTOSTERONE
著者Bennett, M.J, Albert, R.H, Jez, J.M, Ma, H, Penning, T.M, Lewis, M.
登録日1997-03-13
公開日1997-10-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.
Structure, 5, 1997
4UEI
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BU of 4uei by Molmil
Solution structure of the sterol carrier protein domain 2 of Helicoverpa armigera
分子名称: STEROL CARRIER PROTEIN 2/3-OXOACYL-COA THIOLASE
著者Liu, X, Ma, H, Yan, X, Hong, H, Peng, J, Peng, R.
登録日2014-12-18
公開日2015-12-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Structure and Function of Helicoverpa Armigera Sterol Carrier Protein-2, an Important Insecticidal Target from the Cotton Bollworm.
Sci.Rep., 5, 2015
5J9K
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BU of 5j9k by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) in complex with rice D53 repressor EAR peptide motif
分子名称: Protein TPR1, ZINC ION, rice D53 peptide 794-808
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2016-04-10
公開日2017-07-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JGC
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BU of 5jgc by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L111A, L130A, L179A and I195A mutant
分子名称: Protein TPR1, ZINC ION
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2016-04-20
公開日2017-07-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JA5
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BU of 5ja5 by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L111A and L130A mutant in complex with rice D53 repressor EAR peptide motif
分子名称: Protein TPR1, The rice D53 peptide (a.a. 794-808), ZINC ION
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2016-04-12
公開日2017-07-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JHP
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BU of 5jhp by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L179A and I195A mutant in complex with rice D53 repressor EAR peptide motif
分子名称: Protein TPR1, The rice D53 EAR peptide (794-808)
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2016-04-21
公開日2017-07-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
4ZHE
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BU of 4zhe by Molmil
Crystal structure of the SeMet substituted Topless related protein 2 (TPR2) N-terminal domain (1-209) from rice
分子名称: ASPR2 protein
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2015-04-24
公開日2015-08-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C7E
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BU of 5c7e by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA10 peptide
分子名称: ASPR2 protein, Auxin-responsive protein IAA10, ZINC ION
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2015-06-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C6V
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BU of 5c6v by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis NINJA peptide
分子名称: AFP homolog 2, ASPR2 protein
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2015-06-23
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C7F
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BU of 5c7f by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA1 peptide
分子名称: ASPR2 protein, Auxin-responsive protein IAA1, ZINC ION
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2015-06-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
8Z73
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Crystal Structure of AF9 in complex with H3K9la peptide
分子名称: 1,2-ETHANEDIOL, Histone H3.3C, Protein AF-9
著者Li, H.T, Ma, H.D.
登録日2024-04-19
公開日2025-04-23
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献Crystal Structure of AF9 in complex with H3K9la peptide
To be published

 

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