1WBR
 
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1VPU
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1TVT
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3D32
 | | Complex of GABA(A) receptor-associated protein (GABARAP) with a synthetic peptide | | Descriptor: | CHLORIDE ION, Gamma-aminobutyric acid receptor-associated protein, K1 peptide, ... | | Authors: | Weiergraeber, O.H, Stangler, T, Willbold, D. | | Deposit date: | 2008-05-09 | | Release date: | 2008-08-05 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Ligand Binding Mode of GABA(A) Receptor-Associated Protein.
J.Mol.Biol., 381, 2008
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9HGD
 | | Crystal structure of human GABARAP in complex with cyclic peptide GAB_D23 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | Authors: | Ueffing, A, Wilms, J.A, Willbold, D, Weiergraeber, O.H. | | Deposit date: | 2024-11-19 | | Release date: | 2025-07-09 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Accurate de novo design of high-affinity protein-binding macrocycles using deep learning.
Nat.Chem.Biol., 2025
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9HGC
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5K5G
 | | Structure of human islet amyloid polypeptide in complex with an engineered binding protein | | Descriptor: | HI18, Islet amyloid polypeptide | | Authors: | Mirecka, E.A, Feuerstein, S, Gremer, L, Schroeder, G.F, Stoldt, M, Willbold, D, Hoyer, W. | | Deposit date: | 2016-05-23 | | Release date: | 2016-10-26 | | Last modified: | 2024-11-20 | | Method: | SOLUTION NMR | | Cite: | beta-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor.
Sci Rep, 6, 2016
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4CO7
 | | Crystal structure of human GATE-16 | | Descriptor: | GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 2 | | Authors: | Weiergraeber, O.H, Ma, P, Willbold, D. | | Deposit date: | 2014-01-27 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conformational Polymorphism in Autophagy-Related Protein Gate-16.
Biochemistry, 54, 2015
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8S1M
 | | Crystal structure of human GABARAP fused to EGFR (1076-1099) | | Descriptor: | CHLORIDE ION, Epidermal growth factor receptor,Gamma-aminobutyric acid receptor-associated protein, GLYCEROL | | Authors: | Ueffing, A, Willbold, D, Weiergraeber, O.H. | | Deposit date: | 2024-02-15 | | Release date: | 2024-08-14 | | Last modified: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | GABARAP interacts with EGFR - supporting the unique role of this hAtg8 protein during receptor trafficking.
Febs Lett., 598, 2024
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6Y1A
 | | Amyloid fibril structure of islet amyloid polypeptide | | Descriptor: | AMINO GROUP, Islet amyloid polypeptide | | Authors: | Roeder, C, Kupreichyk, T, Gremer, L, Schaefer, L.U, Pothula, K.R, Ravelli, R.B.G, Willbold, D, Hoyer, W, Schroder, G.F. | | Deposit date: | 2020-02-11 | | Release date: | 2020-03-04 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-beta fibrils.
Nat.Struct.Mol.Biol., 27, 2020
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3DOW
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1YO4
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5LTL
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2OJ2
 | | NMR Structure Analysis of the Hematopoetic Cell Kinase SH3 Domain complexed with an artificial high affinity ligand (PD1) | | Descriptor: | Hematopoetic Cell Kinase, SH3 domain, artificial peptide PD1 | | Authors: | Schmidt, H, Hoffmann, S, Tran, T, Stoldt, M, Stangler, T, Wiesehan, K, Willbold, D. | | Deposit date: | 2007-01-12 | | Release date: | 2007-01-30 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of a Hck SH3 Domain Ligand Complex Reveals Novel Interaction Modes
J.Mol.Biol., 365, 2007
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6R4R
 | | Cryo-EM Structure of the PI3-Kinase SH3 Domain Amyloid Fibril | | Descriptor: | Phosphatidylinositol 3-kinase regulatory subunit alpha | | Authors: | Roeder, C, Vettore, N, Mangels, L.N, Gremer, L, Ravelli, R.B.G, Willbold, D, Hoyer, W, Buell, A.K, Schroder, G.F. | | Deposit date: | 2019-03-23 | | Release date: | 2019-08-28 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy.
Nat Commun, 10, 2019
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1FI0
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1KIK
 | | SH3 Domain of Lymphocyte Specific Kinase (LCK) | | Descriptor: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK | | Authors: | Briese, L, Willbold, D. | | Deposit date: | 2001-12-03 | | Release date: | 2001-12-12 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure determination of human Lck unique and SH3 domains by nuclear magnetic resonance spectroscopy.
Bmc Struct.Biol., 3, 2003
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1KOT
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1KZV
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1KZT
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1KZS
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5OQV
 | | Near-atomic resolution fibril structure of complete amyloid-beta(1-42) by cryo-EM | | Descriptor: | Amyloid beta A4 protein | | Authors: | Gremer, L, Schoelzel, D, Schenk, C, Reinartz, E, Labahn, J, Ravelli, R, Tusche, M, Lopez-Iglesias, C, Hoyer, W, Heise, H, Willbold, D, Schroeder, G.F. | | Deposit date: | 2017-08-14 | | Release date: | 2017-09-13 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Fibril structure of amyloid-beta (1-42) by cryo-electron microscopy.
Science, 358, 2017
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2YOM
 | | Solution NMR structure of the C-terminal extension of two bacterial light, oxygen, voltage (LOV) photoreceptor proteins from Pseudomonas putida | | Descriptor: | SENSORY BOX PROTEIN | | Authors: | Rani, R, Lecher, J, Hartmann, R, Krauss, U, Jaeger, K, Willbold, D. | | Deposit date: | 2012-10-25 | | Release date: | 2013-07-10 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | Conservation of Dark Recovery Kinetic Parameters and Structural Features in the Pseudomonadaceae "Short" Light, Oxygen, Voltage (Lov) Protein Family: Implications for the Design of Lov-Based Optogenetic Tools.
Biochemistry, 52, 2013
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2YON
 | | Solution NMR structure of the C-terminal extension of two bacterial light, oxygen, voltage (LOV) photoreceptor proteins from Pseudomonas putida | | Descriptor: | SENSORY BOX PROTEIN | | Authors: | Rani, R, Hartmann, R, Lecher, J, Krauss, U, Jaeger, K, Willbold, D. | | Deposit date: | 2012-10-25 | | Release date: | 2013-07-10 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Conservation of Dark Recovery Kinetic Parameters and Structural Features in the Pseudomonadaceae "Short" Light, Oxygen, Voltage (Lov) Protein Family: Implications for the Design of Lov-Based Optogenetic Tools.
Biochemistry, 52, 2013
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3ZUA
 | | A C39-like domain | | Descriptor: | ALPHA-HEMOLYSIN TRANSLOCATION ATP-BINDING PROTEIN HLYB | | Authors: | Lecher, J, Schwarz, C.K.W, Stoldt, M, Smits, S.S.H, Willbold, D, Schmitt, L. | | Deposit date: | 2011-07-18 | | Release date: | 2012-08-01 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | An Rtx Transporter Tethers its Unfolded Substrate During Secretion Via a Unique N-Terminal Domain.
Structure, 20, 2012
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