1AP0
STRUCTURE OF THE CHROMATIN BINDING (CHROMO) DOMAIN FROM MOUSE MODIFIER PROTEIN 1, NMR, 26 STRUCTURES
Summary for 1AP0
| Entry DOI | 10.2210/pdb1ap0/pdb |
| Descriptor | MODIFIER PROTEIN 1 (1 entity in total) |
| Functional Keywords | chromatin-binding, protein interaction motif, alpha+beta |
| Biological source | Mus musculus (house mouse) |
| Cellular location | Nucleus (By similarity): P83917 |
| Total number of polymer chains | 1 |
| Total formula weight | 8694.56 |
| Authors | Ball, L.J.,Murzina, N.V.,Broadhurst, R.W.,Raine, A.R.C.,Archer, S.J.,Stott, F.J.,Murzin, A.G.,Singh, P.B.,Domaille, P.J.,Laue, E.D. (deposition date: 1997-07-22, release date: 1998-07-22, Last modification date: 2024-05-22) |
| Primary citation | Ball, L.J.,Murzina, N.V.,Broadhurst, R.W.,Raine, A.R.,Archer, S.J.,Stott, F.J.,Murzin, A.G.,Singh, P.B.,Domaille, P.J.,Laue, E.D. Structure of the chromatin binding (chromo) domain from mouse modifier protein 1. EMBO J., 16:2473-2481, 1997 Cited by PubMed Abstract: The structure of a chromatin binding domain from mouse chromatin modifier protein 1 (MoMOD1) was determined using nuclear magnetic resonance (NMR) spectroscopy. The protein consists of an N-terminal three-stranded anti-parallel beta-sheet which folds against a C-terminal alpha-helix. The structure reveals an unexpected homology to two archaebacterial DNA binding proteins which are also involved in chromatin structure. Structural comparisons suggest that chromo domains, of which more than 40 are now known, act as protein interaction motifs and that the MoMOD1 protein acts as an adaptor mediating interactions between different proteins. PubMed: 9171360DOI: 10.1093/emboj/16.9.2473 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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