5FWN

Imine Reductase from Amycolatopsis orientalis. Closed form in in complex with (R)- Methyltetrahydroisoquinoline

Summary for 5FWN

Entry DOI	10.2210/pdb5fwn/pdb
Descriptor	IMINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... (5 entities in total)
Functional Keywords	imine, amine, nadph, oxidoreductase
Biological source	AMYCOLATOPSIS ORIENTALIS
Total number of polymer chains	2
Total formula weight	62256.02
Authors	Man, H.,Aleku, G.,Turner, N.J.,Grogan, G. (deposition date: 2016-02-18, release date: 2016-06-01, Last modification date: 2024-01-10)
Primary citation	Aleku, G.A.,Man, H.,France, S.P.,Leipold, F.,Hussain, S.,Toca-Gonzalez, L.,Marchington, R.,Hart, S.,Turkenburg, J.P.,Grogan, G.,Turner, N.J. Stereoselectivity and Structural Characterization of an Imine Reductase (Ired) from Amycolatopsis Orientalis Acs Catalysis, 6:3880-, 2016 Cited by DOI: 10.1021/ACSCATAL.6B00782 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.14 Å)

Structure validation