9O0Y
Co-crystal structure of human TREX1 in complex with an inhibitor
This is a non-PDB format compatible entry.
Summary for 9O0Y
| Entry DOI | 10.2210/pdb9o0y/pdb |
| Descriptor | Three-prime repair exonuclease 1, N-[(2,3-dichlorophenyl)methyl]-3,5-difluoro-N-[(pyridin-3-yl)methyl]benzamide, MAGNESIUM ION, ... (6 entities in total) |
| Functional Keywords | trex1, sgc, transport protein, structural genomics, psi-biology, structural genomics consortium, hydrolase-inhibitor complex, hydrolase/inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 3 |
| Total formula weight | 77052.50 |
| Authors | Dehghani-Tafti, S.,Dong, A.,Li, Y.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2025-04-03, release date: 2025-05-21) |
| Primary citation | Dehghani-Tafti, S.,Dong, A.,Li, Y.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) Co-crystal structure of human TREX1 in complex with an inhibitor To be published, |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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